Custom Gastroenterology & Hepatology Models

We provide highly relevant, customizable, robustly validated, and translationally valuable models of gastrointestinal and liver diseases.

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Esophageal Disease Models

Gastrointestinal Disease Models

Liver Disease Models

Biliary Disease Models

Pancreatic Disease Models

Other Digestive Disease Models

Preclinical CRO Services

Advantages

FAQs

Why Are Disease Models Essential for Medical Research?

Disease models now speed medical discovery, allowing controlled settings for disease mechanism, evolution, and treatment. By precisely modeling human disease complexity, these models can help scientists screen for new medicines and nudge drugs forward by evaluating drug safety and effectiveness in the early days. Furthermore, tailored disease models can be customized for particular research needs to further individualized diagnostic and therapeutic interventions.

Ace Therapeutics offers an effective and scalable platform for any kind of research application, from drug target discovery to predictive efficacy testing, that supports scientists’ success in understanding and treating advanced gastrointestinal and liver disorders.

Our Mission

Drive Breakthroughs in Gastroenterology & Hepatology

Esophageal Disease Models

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Ace Therapeutics also offers full-scale esophageal disease modeling services to model the tissue inflammation, motility impairment, bacterial invasion, and inflammation seen in conditions such as GERD and Barrett’s esophagus.

Cell-Based Models
Esophageal Organoid Models
Animal Models

Gastrointestinal Disease Models

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We can offer tailored preclinical gut disease models using CRISPR genome editing, microbiome engineering, and rodent surgery at Ace Therapeutics for fast-track disease discovery and drug discovery.

Liver Disease Models

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Ace Therapeutics’ Hepatology Research Department has developed numerous preclinical liver disease models for compound screening and deep molecular efficacy analysis. For that we can create histology and/or ELISA correlations between research of the biomarker, and parameter you are interested in.

Biliary Disease Models

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Ace Therapeutics specializes in using mouse models to study cholangitis alongside inflammatory bowel disease cases, in humans. We can closely observe and analyze how colitis impacts the metabolism of bile acids and contributes to liver cholestasis molecularly.

Pancreatic Disease Models

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Ace Therapeutics is dedicated to customizing pancreatic disease models, for all facets of illness such, as protein misfolding issues endoplasmic reticulum stress challenges, autophagy dysfunction concerns, and inflammatory signaling abnormalities.

Other Digestive Disease Models

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Ace Therapeutics aims to offer individualized models and solutions for studies and drug development for gastrointestinal diseases.

Esophageal Disease Models
Food Allergy Disease Models
Abdominal Infection Disease Models
Multiple Organ Failure Disease Models

How to Order Our Disease Model Customization Services?

Discuss your specific research needs

Confirm customized quote

Draft agreement and detailed contract

Develop models and conduct tests

Deliver results

What Preclinical CRO Services Can We Provide For You?

We carry out preclinical research utilizing sophisticated disease models to assess the efficacy and safety of prospective drug candidates. Our extensive suite of services encompasses the complete preclinical drug development process.

Our Preclinical CRO Services
Drug R&D services	By Target	COX-2 H2 Receptor Proton Pump ClC-2 Guanylate Cyclase-C NHEs	JAKs Phosphodiesterases 5-HT Receptors S1P Receptors H. pylori
	By Efficacy	Mucosal Protective Agents Antispasmodics
	By Research Phase	GI & Hepatic Targeted Drug Delivery System Development Preclinical GI & Hepatic Toxicology Services Pharmacokinetic Services for GI & Hepatic Disease Drug
IVD R&D services	Biochemical Diagnostic Technology Development Immunodiagnostic Technology Development Molecular Diagnostic Technology Development Diagnostic Imaging Technology Development
Vaccine R&D services	Protein Vaccine Development Nucleic Acid Vaccine Development

Our Advantages

Comprehensive disease coverage: models for conditions like NASH, IBD, GERD, and hepatitis.
Advanced technologies: using organoids, microfluidics, CRISPR, and microbiome engineering for precise modeling.
Custom solutions: tailored models designed to meet specific research needs.

Integrated approach: combining genomics, bioinformatics, and metabolomic analysis for comprehensive insights.
Translational relevance: high applicability of their models to clinical scenarios, enhancing preclinical research outcomes.

FAQs

Q: Can your models support drug efficacy and safety evaluation?

A: Sure, we have preclinical test models in which we can assess drug efficacy, toxicology, pharmacodynamics, and pharmacokinetics.

Q: Do your liver models account for immune system interactions?

A: Our models include immune system components to study immune-related liver conditions and the effects of immunotherapies.

Q: What endpoints are assessed in your GI and liver disease models?

A: We consider multiple endpoints such as inflammatory markers, fibrosis, microbiome composition, and metabolic profile so that data is taken in an inclusive way.

Q: How do I request a customized model?

A: You can discuss your research needs with us, confirm a quote, draft a contract, and we will develop the models and provide results.

Q: How long does it take to build custom model?

A: It depends on the level of modelling but we can complete it quickly within your research deadlines.

Q: What are the common applications of your models?

A: Our models are employed in drug discovery, toxicology testing, and the physiology of disease.

Our products and services are for research use only and can not be used for diagnostic or other purposes.