Ace Therapeutics has extensive hands-on experience in the field of experimental model construction for liver disease. Our scientists will provide you with the most scientific experimental model construction service for liver cirrhosis.
Liver cirrhosis is the ultimate pathological outcome of various chronic liver diseases. Experimental models of liver cirrhosis are an important tool for in-depth understanding and research of liver cirrhosis. Based on our advanced technology platform and comprehensive service system, we provide scientific and accurate liver cirrhosis model construction services for liver cirrhosis researchers worldwide.
What Can We Do?
Experimental models of liver cirrhosis are important experimental tools for studying liver cirrhosis. We offer a wide range of in vitro and in vivo experimental models for liver cirrhosis to meet the needs of different studies. Our scientists will construct suitable cirrhosis models for you according to your experimental requirements.
- In Vitro Experimental Models
We have an abundance of hepatocyte lines that can be used to prepare different experimental models of liver cirrhosis in vitro.
- In Vivo Experimental Models
We have now established a well-established protocol for the construction of in vivo experimental models of cirrhosis to support the study of different cirrhotic conditions.
- Chemical-induced Animal Models of Liver Cirrhosis
We can induce liver cirrhosis by activating hepatic stellate cells through direct damage to hepatocytes caused by CCl4, thioacetamide, dimethylnitrosamine, dioxin, sodium arsenate, and ethanol and by triggering a secondary inflammatory response in the liver.
- Diet-induced Animal Models of Liver Cirrhosis
We can induce experimental models of liver cirrhosis by special dietary regimens such as choline deficiency, L amino acid definition, methionine deficiency diet, and high fat diet.
- Surgery-induced Animal Models of Liver Cirrhosis
We can induce liver cirrhosis by bile duct ligation leading to extrahepatic bile duct obstruction, bile stasis, biliary epithelial cell, and hepatocyte damage.
- Immune Reaction-induced Animal Models of Liver Cirrhosis
Based on antigen-antibody reactions, we can form immune complexes through plant proteins such as plant protein concanavalin A and xenogenic serum. These immune complexes are deposited around the portal and central venous regions causing allergic reactions and inflammation which in turn stimulate collagen secretion by hepatic stellate cells and the formation of liver cirrhosis.
Ace Therapeutics has a team of professionals in the field of liver cirrhosis model construction. Our scientists will customize a cirrhosis model just for you according to your needs. If you would like to learn more about our services, please feel free to contact us.
Related Services
Our products and services are for research use only and can not be used for diagnostic or other purposes.
