Integrated R&D Services

Drug R&D Services
- By Target
  - COX-2
  - H2 Receptor
  - Proton Pump
  - ClC-2
  - Guanylate Cyclase-C
  - NHEs
  - JAKs
  - Phosphodiesterases
- By Research Phase
IVD R&D Services
Vaccine R&D Services
Preclinical Gastroenterology & Hepatology CRO Services
- Preclinical Gastroenterology CRO Services
- Preclinical Hepatology CRO Services

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Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Drug R&D Services in Gastroenterology and Hepatology

Inquiry

Ace Therapeutics stands as a premier preclinical contract service provider dedicated to driving drug development in the field of gastroenterology & hepatology. Our expertise lies in understanding disease mechanisms and drug targets, enabling us to deliver holistic solutions for a broad spectrum of digestive system disorders. We offer comprehensive drug development services, from target identification and validation to preclinical testing.

Molecule Types of Drugs We Can Develop

Types of Drugs	Service Details
Small Molecule Compound Development	We have expertise in designing and synthesizing small molecule compounds that target specific pathways involved in digestive disorders.
Hormone Drug Development	Our team is skilled at formulating and optimizing hormone-based drugs to regulate digestive system functions and address hormonal imbalances related to gastrointestinal disorders.
Interferon Drug Development	We have experience developing interferon-based drugs, which play a crucial role in modulating the immune response and treating conditions such as viral hepatitis and inflammatory bowel disease.
Antibody Development	Our capabilities extend to antibody development, where we harness the power of targeted antibodies to selectively bind to disease-specific antigens, offering potential therapeutic options for digestive disorders.
Nucleic Acid Drug Development	We possess expertise in nucleic acid-based drug development, including RNA interference (RNAi) and antisense oligonucleotide (ASO) technologies, which hold promise in regulating gene expression and targeting specific disease-causing genes in digestive disorders.

Our Expertise in Drug Development for Gastrointestinal and Hepatic Diseases

Targets of Drugs Efficacy of Drugs

COX I/II
H2 Receptor
Proton Pump
Chloride Channel
Guanylate Cyclase-C

NHE3
JAKs
Phosphodiesterase
Peripheral Opioid Receptor
Cholinergic Receptor

Serotonin
S1P Receptor
Helicobacter pylori
HBV & HCV
Cytokines

Anti-Inflammatory
Gastric Mucosal Protective
Gastrointestinal Antispasmodic
Antacids
Immunomodulatory

Antidiarrheal
Digestion Aid
Gastrointestinal Promotility
Laxative

Antidiarrheal
Gallstone Dissolution
Antibacterial
Antiviral

Our Platforms for Gastrointestinal and Hepatic Disease Drug Development

Compound Synthesis

Through advanced synthetic organic chemistry techniques, our lab is able to help customers efficiently design and optimize small molecule libraries targeting specific digestive disease pathways.

Protein Expression & Purification

Leveraging mammalian, bacterial and baculovirus cell-based systems, we can express and purify recombinant proteins involved in disease processes.

Pharmacodynamic Research

We utilize both in vitro and in vivo models to investigate the pharmacodynamic properties of potential drug candidates.

Pharmacokinetic Research

Through integrated analytical techniques and validated bioanalytical methods, we can conduct thorough PK assessments to help you understand ADME properties.

Toxicology Research

Our rigorous and specialized safety assessment strategies fully evaluate the lead candidates' toxicological profiles.

Highlights of Our Drug R&D Services in Hepatology and Gastroenterology

Our team has a deep understanding and extensive experience in advancing drug development for GI, liver, pancreatic, and other diseases.
From compound synthesis to preclinical pharmacology studies, our services encompass the entire drug development lifecycle.
Our specialization lies in the development of targeted therapies that specifically address the disease pathways and molecular targets associated with digestive disorders.

At Ace Therapeutics, our experts combine extensive scientific knowledge with state-of-the-art technologies to accelerate the drug development process and bring effective treatments to market faster. If you're looking to optimize candidates or seeking collaboration, please contact us and discover how we can help advance your digestive disease drug development initiatives.

Our products and services are for research use only and can not be used for diagnostic or other purposes.