Custom Animal Model Development

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Cardiovascular disease is a combination of biochemical, physiological, and pathological processes that result from the interaction of genetic and environmental factors. Ace Therapeutics has been involved in cardiovascular disease research for many years, and we are able to provide a wide range of animal model development services for cardiovascular disease research to validate the effectiveness of different preventive and therapeutic approaches.

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Advantages of Animal Models

Undoubtedly, the main advantage of animal models is that we can use animal models to set up different variables and control groups, which can strictly control the experimental conditions and enhance the stability and accuracy of experimental data. Secondly, animal models can overcome the shortcomings of certain human diseases, such as long incubation period, long duration and low incidence rate, which is conducive to the conduct of experiments and daily management.

Fig. 1 Schematic illustration of the pathogenesis of cardiovascular disease in rheumatoid arthritis. (Shao Y, et al., 2023)

Ace Therapeutics uses various types of animal-specific hematology analyzers, biochemical analyzers, and small animal PET/MRI imaging systems and other instruments to carry out experiments including modeling, surgery, drug administration, sampling, and physiological and biochemical index testing of common laboratory animals such as rats, mice, nude mice, guinea pigs and rabbits. We can provide a variety of animal model construction services as listed below.

We provide scientific research project consultation, experimental protocol customization, and subject experimental operations for each customer to meet their individual needs. The common study endpoints for animal model development are as follows:

Ace Therapeutics is dedicated to providing a wide range of specialized animal models to advance basic research, novel drug discovery and diagnostic method development for cardiovascular disease. If you are interested in our services, please don't hesitate to contact us.

1. Shao, Y.; et al. Clinical prediction models of rheumatoid arthritis and its complications: focus on cardiovascular disease and interstitial lung disease. Arthritis Res Ther. 2023, 25(1):159.