Cat.#: ASSD-140
| Description | A2B covalent ligand selectively targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays, allowing for novel ways to interrogate the A2BAR. Apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action. Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors. |
| Size | 50 μg |
| Chemical Name | 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonyl fluoride |
| Molecule Weight | 352.3 |
| Molecular formula | C14H13FN4O4S |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
| Cat.# | Name | Size | Price |
|---|---|---|---|
| ASSD-215 | 1-Pyrenylmethyl Methanethiosulfonate (AC215) | 10 mg | inquiry |
| ASSD-177 | Fluorescein 5-Maleimide (AC177) | 25 mg | inquiry |
| ASSD-170 | BAPTA-AM (AC170) | 25 mg | inquiry |
| ASSD-103 | DAPI Staining Solution (1mg/mL) (AC103) | 1 mL, 5 mL, | inquiry |
| ASSD-174 | Coomassie Blue R-250 (AC174) | 25 g, 100 g | inquiry |
| ASSD-110 | Picro Sirius Red Stain Kit (AC110) | 1 kit, 100 tests | inquiry |
| ASSD-132 | Congo Red (AC132) | 100 mg, 1g | inquiry |
| ASSD-143 | Fluorescently labeled Muscimol TMR-X conjugate (AC143) | 1mg | inquiry |
| ASSD-214 | 8-Aminopyrene-1,3,6-trisulfonic acid trisodium salt (AC214) | 10 mg | inquiry |
| ASSD-163 | Ponceau S sodium salt (AC163) | 25 g | inquiry |
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