Cat.#: ASSD-140
| Description | A2B covalent ligand selectively targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays, allowing for novel ways to interrogate the A2BAR. Apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action. Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors. |
| Size | 50 μg |
| Chemical Name | 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonyl fluoride |
| Molecule Weight | 352.3 |
| Molecular formula | C14H13FN4O4S |
| Purity | >95% |
| Solubility | Soluble in DMSO |
| Storage | Store at -20° C |
| Shipping | Shipped at 4°C |
| Cat.# | Name | Size | Price |
|---|---|---|---|
| ASSD-146 | Pyronin Y (AC146) | 1 g, 5g | inquiry |
| ASSD-122 | Fluorescent β2 antagonist [(±)-propranolol] (AC122) | 500 μg | inquiry |
| ASSD-151 | Acid Fuchsin (AC151) | 25 g | inquiry |
| ASSD-126 | Fluorescent H2 antagonist [aminopotentidine] (AC126) | 50 μg | inquiry |
| ASSD-132 | Congo Red (AC132) | 100 mg, 1g | inquiry |
| ASSD-129 | Fluorescent 5-HT1A antagonist [NAN-190] (AC129) | 50 μg | inquiry |
| ASSD-217 | t-Boc-MTSEA-Fluorescein (AC217) | 10 mg | inquiry |
| ASSD-208 | NBD-X, succinimidyl ester (AC208) | 100 mg | inquiry |
| ASSD-113 | Thionin acetate salt (AC113) | 5 g | inquiry |
| ASSD-120 | Fluorescent adenosine antagonist [XAC] (AC120) | 500 μg | inquiry |
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