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A2B covalent ligand (AC140)
Cat.#: ASSD-140
Specifications
Description A2B covalent ligand selectively targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays, allowing for novel ways to interrogate the A2BAR. Apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action.
Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors.Size 50 μg Chemical Name 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonyl fluoride Molecule Weight 352.3 Molecular formula C14H13FN4O4S Purity >95% Solubility Soluble in DMSO Storage Store at -20° C Shipping Shipped at 4°C Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
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Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.
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