Cat.#: ASSD-140
Description | A2B covalent ligand selectively targets lysine residue(s) on the receptor and binds persistently in radioligand displacement and wash-out assays, allowing for novel ways to interrogate the A2BAR. Apparent pKi values at A2BARs are 8.10 and 9.17 (after 4h), where a Ki shift indicates a covalent mode of action. Displays ~100 -fold selectivity for A2B compared to A1, A2A and A3 receptors. |
Size | 50 μg |
Chemical Name | 4-(2,6-dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)benzenesulfonyl fluoride |
Molecule Weight | 352.3 |
Molecular formula | C14H13FN4O4S |
Purity | >95% |
Solubility | Soluble in DMSO |
Storage | Store at -20° C |
Shipping | Shipped at 4°C |
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