Therapeutic Areas
// Our Therapeutic Areas

Explore Our Expertise in IBD

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Ace Therapeutics scientists’ deep experience across a broad range of IBD will guide you to the most appropriate assays based on your therapeutic area of focus or target class of interest. Our teams stay at the forefront of therapeutic knowledge so they can generate the most actionable data for your research. Our cross-disciplinary expertise enables us to work efficiently with fast turnaround times—without compromising quality.

Ulcerative Colitis Research Services

Our expertise in preclinical ulcerative colitis (UC) research and consistent track record of success as a full-service CRO provides the knowledge and flexibility to adapt to the unique needs of each experiment. Our team of experts will guide you through the study design process, ensuring that scientific questions are addressed and the appropriate experimental model is used.

  • Ulcerative Proctitis
  • Left-sided Colitis
  • Extensive Colitis

Crohn's Disease Research Services

Ace Therapeutics is at the forefront of preclinical Crohn's disease (CD) research, combining long-standing expertise with advanced scientific tools. Our approach enables the detection of nuanced responses in animal models, providing clear insight into the efficacy and safety of novel Crohn's disease therapies.

  • Ileocolitis
  • Crohn's Ileitis
  • Gastroduodenal Crohn's Disease
  • Jejunoileitis
  • Chronic Granulomatous Disease

Research Services for Intestinal Complications of IBD

Our team of experts is committed to advancing the science of intestinal complications of IBD by providing innovative solutions and new technologies for your drug programs. Our scientists will work with you to understand your target and pathway, determine the best medicinal chemistry strategy for your program, and develop robust custom assays along with our unmatched portfolio of validated, ready-to-use assays.

  • Intestinal Perforation
  • Intestinal Stricture
  • Fistulating Crohn's Disease
// Our Platforms

Advanced Technology Methods to Support IBD Research

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Colonoscopy in Animals

Our team of experienced experts can perform colonoscopy on various species including mice and rats. Using state-of-the-art equipment and techniques, we help clients visualize the inside of the colon, perform biopsies for further analysis, and monitor disease progression over time.

Imaging Technologies

Ace Therapeutics has well-established imaging technology platforms to address clients' imaging needs in animal models of IBD. Our advanced imaging techniques not only allow direct visualization of intestinal inflammation, but also enable molecular imaging and targeting of specific alterations of the inflamed murine mucosa.

Gut Microbiota Studies

Ace Therapeutics provides integrated research solutions for the study of the gut microbiota in IBD, employing advanced metabolomics and high-throughput sequencing technologies. We aim to provide key insights into the pathogenesis of IBD and data to support the development of microbiome-based diagnostics and therapeutics for IBD.

Intestinal Barrier Dysfunction Research

Our team of experts provides in-depth characterization of intestinal epithelial barrier genes in IBD animals, incorporating genetic and transcriptomic approaches to help clients better understand the genes and intestinal epithelial barrier components associated with the disease.