Preclinical Ophthalmic Drug Development Services ace

Ocular Insert Development Services for Drug Delivery

The ocular insert may improve bioavailability by increasing its contact time with the corneal surface. As a full-service ophthalmic product preclinical development CRO, Ace Therapeutics provides one-stop ocular insert development services. As a global provider of high-quality ocular diseases, we have successfully developed various ocular inserts in cooperation with our clients. Our one-stop ocular delivery system development services can meet all your research needs.

Development of an Ocular Insert Drug Delivery System for Ocular Disease

Advantages of Ocular Insert

The ocular insert is a sterile, multi-layered, thin, drug-impregnated device of solid or semi-solid consistency that represents a major advance in ocular disease. It consists of multiple layers of biodegradable implantable components that are controlled, delayed, or sustained release. Thus providing an attractive alternative to reducing corneal dwell times. It has multiple advantages: 1) It prolongs the residence time in the eye and improves bioavailability. 2) The drug release rate is slow and constant. 3) Accurate dosage. 4) Less systemic absorption. 5) Low incidence of side effects and good patient compliance. 6) Increased possibility of targeting internal ocular tissues. 7) Low risk of allergic reactions.

Fig. 1. Classification of ocular inserts. (Kumari A, et al., 2010)

What Is Ace Therapeutics Doing for Ocular Drug Delivery System Development?

Ocular implants are the most advanced technology in eye disease treatment. Ace Therapeutics has been working on developing a new ocular delivery system to improve ocular bioavailability. Our researchers have worked hard to avoid frequent dosing by releasing the drug at a controlled rate through the ocular insert. At Ace Therapeutics, we provide high-quality ocular insert development services for our clients.

One-stop Ocular Insert Drug Delivery System Development Service for Ocular Disease

Ace Therapeutics provides a one-stop solution for ocular insert development, and our experienced scientists provide you with the fastest project turnaround and professional technical support. To meet different customers' research needs, we offer the following ocular insert service development services, including but not limited to:

Preparation of ocular inserts

Solvent casting
Glass substrate technology
Melting extrusion technology

Evaluation of ocular inserts

Weight uniformity
Moisture absorption rate
Thickness
Swelling index
Drug Content and Uniformity
Surface pH
Folding resistance

In vitro diffusion studies
Ocular pharmacodynamic evaluation of ocular inserts

Our Capabilities

Additionally, Ace Therapeutics offers the following other ocular delivery systems that may be of interest to you, ask our scientists for details.

As a contract provider of solutions for ocular diseases, in order to better understand unmet needs, successful delivery of ocular drug delivery systems. Ace Therapeutics provides one-stop ocular insert development services for our customers. If you are interested in our services or need more detailed information, please feel free to contact us. Our experienced scientists are ready to help you!

Reference

Kumari A, Sharma PK, Garg VK, et al. Ocular inserts - Advancement in therapy of eye diseases. J Adv Pharm Technol Res. 2010 Jul;1(3):291-6.

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