Ischemic stroke is a leading cause of death and disability, yet little is known about the effectiveness and safety of ischemic stroke treatment. The key challenge in stroke treatment is to determine the most effective way to implement the currently available effective interventions. Evaluating the safety of compounds early in the stroke drug discovery and development phase allows pharmaceutical companies to exclude unlikely compounds early in the drug discovery process, freeing up more time and resources to develop more promising lead candidates for stroke.
Ace Therapeutics is the ideal partner to help you evaluate the safety of your stroke drugs. With a dedicated team of scientists and hands-on experience in stroke drug safety evaluation, Ace Therapeutics provides you with high-quality data and fast turnaround times to support every drug safety evaluation study.
We use advanced in vitro models and animal models of stroke to assess the safety of stroke drugs earlier in the discovery process more accurately. Whether you are developing an innovative small molecule or an advanced biological drug candidate, you can rely on our safety evaluation team to develop a program that meets your specific needs.
General Toxicology
We offer a full suite of general toxicology studies, including acute/single-dose, subchronic and chronic toxicity studies.
We work with you to develop, optimize, and implement innovative techniques to assess the potential neurotoxic effects of your stroke medications, including adverse effects on nervous system chemistry, structure, or function.
Genetic Toxicology
Our safety evaluation team provides in vitro and in vivo genotoxicity screening assays for stroke drug discovery programs to determine the presence of potential genetic damage or genotoxic impurities.
Safety Pharmacology
We provide in vitro and in vivo safety pharmacology studies to investigate the potential toxicity of stroke drugs to the central nervous system, cardiovascular system, and respiratory system to support drug discovery.
Developmental and Reproductive Toxicology
We provide animals for reproductive toxicity testing. We observe the effects of stroke drugs on reproductive function and developmental processes in mammals and predict possible adverse effects on germ cells, conception, pregnancy, delivery and parental reproductive function, as well as embryonic, fetal and postnatal development of the offspring.
Carcinogenicity Testing
We provide animals to test whether stroke drugs induce a risk of tumor development in animals.
Specialized Toxicity Testing
We can perform special toxicity studies, including local irritation, sensitization, phototoxicity and ocular toxicity studies, depending on the needs of your project.
Ace Therapeutics's safety assessment services are fully integrated with our drug efficacy testing and supported by our DMPK and bioanalytical teams, saving you time and costs and accelerating stroke drug development. If you are interested in our services, please do not hesitate to contact us!
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.