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- ADME/DMPKDrug Efficacy Testing
- Cerebral Infarct Size Measurement
- Histological Assessment
- Physiological Monitoring
- Behavioral TestingBrain Imaging
- Cerebral Blood Flow Monitoring
- Brain Edema Measurement
- Assessment of Blood-Brain Barrier
- Assessment of Leukocyte-Platelet Aggregates
- Quantitative Analysis of Protein and mRNA Expression
Safety AssessmentIn Vitro Pharmacology- Cell Viability Assay
- Caspase-3 Activity Assay
- In Vitro Neuroinflammatory Models and Assays
- Excitotoxicity In Vitro Assay
- Cell-Based Mitochondrial Function Assay
- In Vitro Oxidative Stress Assay
- Ischemia-Triggered Glutamate Excitotoxicity
- NMDA Receptor-mediated Excitotoxicity
- AMPA Receptor-mediated Excitotoxicity
Molecular Mechanism of Oxidative StressNeuroinflammatory Mechanisms- Ischemia-Reperfusion Injury
Cell Death Mechanism- Autophagy MechanismApoptotic Mechanism
- Ferroptosis Pathways
- Necroptosis Signaling Pathways
Epigenetic Mechanism- Gut Microbiota
- Animal Modeling of Stroke
- Animal Modeling of Ischemic StrokeAnimal Modeling of Hemorrhagic StrokeIn Vitro Modeling of Stroke
- In Vitro Modeling of Ischemic Stroke
- In Vitro Modeling of Hemorrhagic Stroke
- Small-Molecule Antiplatelet DrugsNeuroprotective PeptidesMonoclonal Antibodies for StrokeStem Cell-Based Therapies for StrokeDrug Delivery SystemsInquiry
ADME/DMPK Services for Stroke Drugs
Drug metabolism and pharmacokinetics (DMPK) play a key role throughout the stroke drug development process by focusing on the absorption, distribution, metabolism, excretion (ADME), and pharmacokinetic (PK) properties of a stroke drug candidate to help characterize the drug candidate's pharmacology.
At Ace Therapeutics, we have built an experienced DMPK team that can help you design the optimal ADME/DMPK program for your stroke drug discovery and development needs. We can design flexible DMPK screening cascades to support stroke drug development programs, including customized method development.
Our highly trained and experienced scientific team uses validated methodologies that enable all aspects of ADME testing and PK testing, enabling the evaluation of DMPK properties and toxicity of stroke drug candidates in a high data quality, cost-effective manner. Our DMPK services are designed to minimize stroke compound failures, determine the efficacy of targets with acceptable safety profiles, optimize PK parameters, and reduce drug-drug interactions (DDIs).
Custom ADME/DMPK Services
Ace Therapeutics has a range of capabilities and experience to support the discovery and development of stroke drug candidates. We provide rapid turnaround of high-quality critical DMPK datasets to support key decisions that advance the further development of potential stroke therapeutics.
- High-Throughput ADME Screening Services for Stroke Drug Discovery and Development
- In Vitro ADME Services for Stroke Drug Discovery and Development
- In Vivo ADME Services for Stroke Drug Discovery and Development
- PK/TK Analysis in Stroke Drug Discovery and Development
- Trans-BBB PK Analysis in Stroke Drug Discovery and Development
- PK/PD Analysis Service for Stroke Discovery and Development
- Bioanalytical Services for Stroke Drugs
- Metabolite Identification and Profiling in Stroke Drug Discovery and Development
- Neurochemistry Service in Stroke Drug Discovery & Development
Why Choose Us
- Committed to quality and efficiency, we work closely with clients to provide customized ADME DMPK solutions for different phases of stroke drug discovery and development based their projects.
- Our services cover the entire DMPK spectrum, from in vitro PK and DDI to in vivo DMPK, biotransformation and metabolite identification, and discovery bioanalysis.
- We use state-of-the-art technology to provide you with reliable data to support the development of safe and effective stroke drugs.
- Our DMPK lab can help you save time, reduce costs, and conserve resources in your stroke drug discovery efforts.
As a stroke drug DMPK service provider, Ace Therapeutics is committed to being the partner of choice for stroke drug discovery and development by providing all clients with high-quality data, precise R&D strategies, and exceptional service to meet each client's unique needs. If you are interested in our services, please do not hesitate to contact us!
All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.
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