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Immortalized Human Brain Microvascular Endothelial Cells- Ras
Cat.#: BBM-C-152
Specifications
Description Immortalized Human Brain Microvascular Endothelial Cells- Ras from Ace Therapeutics are a specialized cell line developed by immortalizing primary cells using serial passaging and transduction with recombinant lentiviruses carrying the Ras gene. These cells have been extensively characterized and demonstrated to maintain the immune barrier properties of primary HBMECs. Each vial contains at least 1×10^6 cells per ml and is delivered frozen. Species Human Source Brain Recommended Medium It is recommended to use Immortalized Human Brain Microvascular Endothelial Cells Medium Kit for culturing in vitro. Cell Type Endothelial Disease Normal Quality Control Real Time PCR was used to quantify Ras gene expression in immortalized cell line. Shipping and Storage Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage.
Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended.Applications Immortalized Human Brain Microvascular Endothelial Cells (IM-HBMECs) offer a cost-effective and practical solution for constructing in vitro models of the blood-brain barrier (BBB). These immortalized cells exhibit exceptional fidelity in terms of barrier resistance, immune migration profiles, and responsiveness to inflammatory cytokines. With their specialized BBB endothelial phenotype, this newly established human cell line provides a readily available in vitro model for studying the properties of the human BBB. IM-HBMECs are particularly valuable for investigating central nervous system infections, offering a valuable alternative to primary brain endothelial cells as a reliable model for studying the blood-brain barrier in such studies. Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
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