Heart valve disease is a disorder of the mitral, tricuspid, aortic and other valves caused by a variety of reasons that can lead to cardiac dysfunction, arrhythmia or heart failure. Ace Therapeutics provides a wide range of research services for animal model construction and artificial heart valve development to promote new breakthroughs and progress in the field of heart valve disease.
When the heart valves get damaged or diseased, the heart cannot pump blood efficiently, which can cause heart failure, cardiac arrest, or even death. Heart valve disease can be triggered by congenital heart disease, endocardial infections, degenerative diseases, or other types of heart condition. For substantial heart valve injuries, the usual therapy strategy is to repair the heart valves using surgical or interventional therapies.
Fig. 1 Severe valvular heart disease. (Ajmone Marsan N, et al., 2023)
Ace Therapeutics is able to provide comprehensive support for clients to accelerate basic research and artificial heart valve development.
Research Models
Basic Research
Artificial Valves
We deeply understand the importance of animal disease models for heart valve disease research. In order to assist our clients in researching heart valve disease, we are able to provide animal model development and research services.
Custom Animal Models of Heart Valve Disease
For different kinds of induction mechanisms, we can provide customized animal model development services to meet the individual needs of customer research.
Transgenic Animal Model Development Services
Heart valve disease is a disease that can be induced by congenital genetic abnormalities, and research on the genes of congenital heart valve disease has made some progress in recent years. We can provide construction services of transgenic or knockout animal models to help research on congenital heart valve disease, including but not limited to the following genes:
Heart valve disease can be induced by a variety of factors and has a complex pathogenesis. We offer a variety of basic research services to help advance the study of heart valve disease.
Pathogenesis Research Services
Factors contributing to heart valve disease include rheumatic fever, bacterial endocarditis, and degenerative valve changes. Based on our specialized multi-omics research platform, we can provide individualized research services to help clients explore the pathogenesis of heart valve disease.
Pathology and Imaging Services
For animal studies of heart valve disease, our advanced pathology and imaging technology platforms enable monitoring and therapeutic evaluation of animal models of the disease.
Since heart valve disease is an organic pathology that is difficult to treat with pharmacologic strategies, surgery and interventional therapies have become the mainstay of clinical practice. We are able to provide services for the evaluation and coating modification of prosthetic heart valve materials for heart valve diseases.
Ace Therapeutics has been involved in cardiovascular disease research for many years. With a well-established research technology platform and a professional research team, we are committed to providing high-quality research and development services to our clients. If you are interested in our services for heart valve disease, please don't hesitate to contact us.
Ace Therapeutics offers comprehensive solutions and R&D services to researchers worldwide to advance the field of cardiovascular diseases.
We do not provide medical care for patients.
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