Preclinical Hemorrhagic Stroke Research Services
Hemorrhagic strokes occur when a weakened blood vessel in the brain ruptures, causing bleeding into the surrounding brain tissue. The accumulated blood puts pressure on the nearby brain tissue, leading to compression and potential damage. Treating hemorrhagic strokes can be challenging due to the difficulty in directly accessing and managing the bleeding site within the brain. Supportive therapy, hemostatic therapy, surgery, complication prevention, and rehabilitation treatment are conventional therapeutic strategies for hemorrhagic strokes. There is still a lack of research on pathomechanisms and drug development in hemorrhagic stroke.
Explore Our Expertise in Hemorrhagic Stroke
Ace Therapeutics is at the forefront of preclinical hemorrhagic stroke research services, leveraging our extensive expertise alongside cutting-edge scientific tools. Our comprehensive approach allows us to detect subtle responses in animal models, delivering clear insights into the efficacy and safety of new hemorrhagic stroke therapies. Committed to providing high-quality data and robust analysis, we empower confident decision-making, setting your program on a trajectory for success.
Custom Animal Models of Hemorrhagic Stroke
Ace Therapeutics provides customized animal models of hemorrhagic stroke to clients worldwide to help them study the underlying mechanisms of brain injury induced by hemorrhagic stroke and develop new therapies.
Development of Drugs for Hemorrhagic Stroke
Development of Neuroprotective Drugs
Our research services focus on advancing the development of novel neuroprotective drugs for hemorrhagic stroke. We specialize in optimizing calcium channel modulators and novel free radical scavengers with enhanced blood-brain barrier permeability.
Development of Stem Cell-Based Therapies
Our team consists of experts from various fields including biomedical science, neuroscience, and cytology, with a strong background in stem cell research and therapy development. This experience enables us to provide our clients with in-depth research into the pathogenesis of hemorrhagic stroke and the development of stem cell therapies. In addition, we can help our clients develop drug delivery systems that allow stem cells to be targeted to the site of injury in hemorrhagic stroke, improving the efficiency of treatment.
Preclinical Evaluation of Hemorrhagic Stroke Therapeutics
We can measure multiple endpoints to help clients track disease progression and assess the safety and efficacy of stem cell therapy for hemorrhagic stroke.
| Preclinical Evaluation Services | Service Details |
|---|---|
| Behavioral testing services | Provide modified neurological severity scores and multiple behavioral tests to help clients assess changes in sensorimotor and cognitive function before and after drug administration in animal models of hemorrhagic stroke. |
| Measurement of hemorrhagic brain injury | Evaluate indicators of hemorrhagic brain injury, including brain degeneration and lesion size, through histologic examination and magnetic resonance imaging (MRI). |
| Assessment of blood-brain barrier disruption | Assess the effects of drugs on the structural integrity of brain tissue and blood-brain barrier leakage in animal models of hemorrhagic stroke by electron microscopy. |
| Assessment of the therapeutic plasticity of neural stem cells | Assess the ability of stem cells to promote neurogenesis by histochemical staining of proliferating cells, immature neurons, and neuronal precursor markers in animal models of hemorrhagic stroke. |
At Ace Therapeutics, we are dedicated to advancing preclinical research in hemorrhagic stroke. We utilize animal models of hemorrhagic stroke and assay platforms to help you develop effective therapies. As your dedicated preclinical partner, we collaborate closely with you at every stage of the process, offering our expertise in study design, execution, analysis, and interpretation. Contact us today and begin your journey of discovery.
- Kim, J. T., et al. (2022). Recent stem cell research on hemorrhagic stroke: an update. Journal of Korean Neurosurgical Society, 65(2), 161.
