Cat.#: BBM-C-122
Description | Human Brain Microvascular Endothelial Cells (HBMECs), derived from the human brain, are a specific type of brain endothelial cells that play a crucial role in forming the blood-brain barrier (BBB). They prevent the entry of soluble and cellular substances from the blood into the brain and protect it against toxins and immune cells. These brain microvascular endothelial cells have the ability to display cell adhesion molecules on their surface, which control the migration of leukocytes into the brain. Nevertheless, when there are host-pathogen interactions outside the cells, it can activate calcium signaling within the endothelial cells, leading to the penetration of pathogens through the BBB. Human Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from normal human brain cortical tissue. Each vial contains at least 5×10^5 cells per ml and is delivered frozen. |
Species | Human |
Source | Brain |
Recommended Medium | It is recommended to use Human Brain Microvascular Endothelial Cells Medium Kit for culturing in vitro. |
Cell Type | Endothelial |
Disease | Normal |
Quality Control | Human Brain Microvascular Endothelial Cells test negative for bacteria, yeast, fungi, and mycoplasma. |
Shipping and Storage | Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage. Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended. |
Applications | Human brain microvascular endothelial cells can be used to study the molecular and cellular properties of the blood-brain barrier, or in vitro can be used as the model of the blood-brain barrier (BBB) to study neurological diseases. |
Citation Guidance | If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. |
Cat.# | Name | Description | Price |
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BBM-C-142 | Mouse Astrocytes-brain stem from CD1 |
Mouse Astrocytes-brain stem from CD1 (MA-bs) are isolated from embryonic day 15 mouse brain stem. MA-bs are cryopreserved as primary cultures and delivered frozen.
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BBM-C-146 | Sprague-Dawly (SD) Rat Astrocytes |
Characterization: 1. Cell Activity;
– Recovery Viability ≥ 80%.
2. Cell Purity;
– GFAP-positive cells ≥ 70%.
– β-tubulin III- or doublecortin- (Dcx-) positive cells ≤ 10%.
– GalC-positive cells ≤ 10%.
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BBM-C-127 | C57BL/6 Mouse Brain Microvascular Endothelial Cells |
C57BL/6 mouse brain endothelial cells (MBREC) from Ace Therapeutics are isolated from the brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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BBM-C-148 | Rat Astrocytes-adult |
Rat Astrocytes-adult (RA-a) from Ace Therapeutics are isolated from adult CD® IGS rat brains and are cryopreserved after purification. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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BBM-C-144 | Rat Astrocytes |
Rat Astrocytes (RA) from Ace Therapeutics are isolated from postnatal day 2 rat brains and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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BBM-C-124 | Human Astrocytes |
Human Astrocytes from Ace Therapeutics are isolated from the human cerebral cortex, cryopreserved at passage one. Each vial contains at least 5×10^5 cells per ml and is delivered frozen.
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BBM-C-132 | Porcine Brain Microvascular Endothelial Cells |
Porcine Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from healthy porcine brain tissue. Porcine Brain Microvascular Endothelial Cells are grown in T25 tissue culture flasks pre-coated with a gelatin-based solution for 0.5 hours and incubated in Ace Therapeutics’s Culture Complete Growth Medium generally for 3-7 days. Cultures are then expanded. Prior to shipping, cells are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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BBM-C-128 | BALB/c Mouse Brain Microvascular Endothelial Cells |
BALB/c Mouse Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from the brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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BBM-C-133 | Canine Brain Microvascular Endothelial Cells |
Canine Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from the brain of a pathogen-free laboratory beagle dog. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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BBM-C-143 | Mouse Astrocytes-cerebellar from CD1 |
Mouse Astrocytes-cerebellar from CD1 from Ace Therapeutics are isolated from a pathogen-free mouse cerebellar and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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