Products
-
- BBB DamageCategories
- Neurotransmitter Antibodies & Receptor Antibodies
- Ionotropic Receptor AntibodiesMetabotropic Receptor AntibodiesNeurotransmitter AntibodiesTransporter AntibodiesSignal Channel Antibodies
- Calcium Channel AntibodiesChloride Channel AntibodiesDense-Core Vesicles AntibodiesNitric Oxide Channel AntibodiesStroke Pathology Antibodies
- Neurogenesis AntibodiesNeuronal Growth & Development AntibodiesNeuronal Growth & Development AntibodiesNeuronal Metabolism AntibodiesSignal Transduction AntibodiesStroke-Related Cell Markers Antibodies
- Glial Cell Marker AntibodiesNeural Stem Cell Marker AntibodiesNeuron Marker AntibodiesSynaptic Marker AntibodiesCell Death and ApoptosisNeuroinflammationNeuronal Damage and RepairOxidative StressVascular Mechanisms
- 3D BBB Models
- Organ-on-a-Chip BBB ModelsTranswell Models3D BBB Models Culture Substrate
- 3D HydrogelsCollagensAnmial BBB ModelsCell Lines for BBB Modeling
- Immortalized CellsPrimary CellsStem Cells
Human Brain Microvascular Endothelial Cells
Cat.#: BBM-C-122
Specifications
Description Human Brain Microvascular Endothelial Cells (HBMECs), derived from the human brain, are a specific type of brain endothelial cells that play a crucial role in forming the blood-brain barrier (BBB). They prevent the entry of soluble and cellular substances from the blood into the brain and protect it against toxins and immune cells. These brain microvascular endothelial cells have the ability to display cell adhesion molecules on their surface, which control the migration of leukocytes into the brain. Nevertheless, when there are host-pathogen interactions outside the cells, it can activate calcium signaling within the endothelial cells, leading to the penetration of pathogens through the BBB.
Human Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from normal human brain cortical tissue. Each vial contains at least 5×10^5 cells per ml and is delivered frozen.Species Human Source Brain Recommended Medium It is recommended to use Human Brain Microvascular Endothelial Cells Medium Kit for culturing in vitro. Cell Type Endothelial Disease Normal Quality Control Human Brain Microvascular Endothelial Cells test negative for bacteria, yeast, fungi, and mycoplasma. Shipping and Storage Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage.
Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended.Applications Human brain microvascular endothelial cells can be used to study the molecular and cellular properties of the blood-brain barrier, or in vitro can be used as the model of the blood-brain barrier (BBB) to study neurological diseases. Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
Cat.# Name Description Price BBM-C-133 Canine Brain Microvascular Endothelial Cells Canine Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from the brain of a pathogen-free laboratory beagle dog. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.inquiry BBM-C-144 Rat Astrocytes Rat Astrocytes (RA) from Ace Therapeutics are isolated from postnatal day 2 rat brains and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.inquiry BBM-C-127 C57BL/6 Mouse Brain Microvascular Endothelial Cells C57BL/6 mouse brain endothelial cells (MBREC) from Ace Therapeutics are isolated from the brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.inquiry BBM-C-139 CD1 Mouse Astrocytes CD1 Mouse Astrocytes from Ace Therapeutics are isolated from postnatal day 2 mouse brains. MA is characterized by immunofluorescence with antibodies specific to GFAP. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.inquiry BBM-C-135 Mouse Brain Vascular Pericytes (MBVP) Mouse Brain Vascular Pericytes (MBVP) from Ace Therapeutics are isolated from adult mouse brains and cryopreserved at P2. MBVP express Neural/glial antigen 2 (NG2) and α-smooth muscle actin. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.inquiry BBM-C-124 Human Astrocytes Human Astrocytes from Ace Therapeutics are isolated from the human cerebral cortex, cryopreserved at passage one. Each vial contains at least 5×10^5 cells per ml and is delivered frozen.inquiry BBM-C-146 Sprague-Dawly (SD) Rat Astrocytes Characterization: 1. Cell Activity; – Recovery Viability ≥ 80%. 2. Cell Purity; – GFAP-positive cells ≥ 70%. – β-tubulin III- or doublecortin- (Dcx-) positive cells ≤ 10%. – GalC-positive cells ≤ 10%.inquiry BBM-C-136 Rat Brain Vascular Pericytes (RBVP) Rat Brain Vascular Pericytes (RBVP) from Ace Therapeutics are isolated from adult rat brains and cryopreserved at P2. MBVP expresses Neural/glial antigen 2 (NG2) and α-smooth muscle actin. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.inquiry BBM-C-143 Mouse Astrocytes-cerebellar from CD1 Mouse Astrocytes-cerebellar from CD1 from Ace Therapeutics are isolated from a pathogen-free mouse cerebellar and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.inquiry BBM-C-125 CD1 Mouse Brain Microvascular Endothelial Cells CD1 Mouse Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.inquiry All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
We are committed to accelerating progress in stroke research and drug development.
Copyright © Ace Therapeutics. All rights reserved.0Inquiry Basket