Cat.#: BBM-C-122
Source | Brain |
Disease | Normal |
Species | Human |
Cell Type | Endothelial |
Description | Human Brain Microvascular Endothelial Cells (HBMECs), derived from the human brain, are a specific type of brain endothelial cells that play a crucial role in forming the blood-brain barrier (BBB). They prevent the entry of soluble and cellular substances from the blood into the brain and protect it against toxins and immune cells. These brain microvascular endothelial cells have the ability to display cell adhesion molecules on their surface, which control the migration of leukocytes into the brain. Nevertheless, when there are host-pathogen interactions outside the cells, it can activate calcium signaling within the endothelial cells, leading to the penetration of pathogens through the BBB. Human Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from normal human brain cortical tissue. Each vial contains at least 5×10^5 cells per ml and is delivered frozen. |
Applications | Human brain microvascular endothelial cells can be used to study the molecular and cellular properties of the blood-brain barrier, or in vitro can be used as the model of the blood-brain barrier (BBB) to study neurological diseases. |
Quality Control | Human Brain Microvascular Endothelial Cells test negative for bacteria, yeast, fungi, and mycoplasma. |
Shipping and Storage | Ace Therapeutics ships frozen cells using dry ice. Upon receiving the frozen cells, immediately move them into liquid nitrogen (-180 °C) for storage. Note: Never can cells be kept at -20 °C, and repeated freezing and thawing of cells is not recommended. |
Cat.# | Name | Description | Price |
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BBM-C-146 | Sprague-Dawly (SD) Rat Astrocytes |
Characterization: 1. Cell Activity;
– Recovery Viability ≥ 80%.
2. Cell Purity;
– GFAP-positive cells ≥ 70%.
– β-tubulin III- or doublecortin- (Dcx-) positive cells ≤ 10%.
– GalC-positive cells ≤ 10%.
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inquiry |
BBM-C-125 | CD1 Mouse Brain Microvascular Endothelial Cells |
CD1 Mouse Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from brain tissue of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
|
inquiry |
BBM-C-130 | Bovine Brain Microvascular Endothelial Cells |
Bovine Brain Microvascular Endothelial Cells (BBMVEC) from Ace Therapeutics are isolated from microvessels of the bovine brain. The cells are cryopreserved at the second passage.
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inquiry |
BBM-C-140 | Mouse Astrocytes-hippocampal from CD1 |
Mouse Astrocytes-hippocampal from CD1 from Ace Therapeutics are isolated from postnatal day 2 mouse hippocampus and are cryopreserved as primary cultures. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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inquiry |
BBM-C-137 | Rabbit Cerebrovascular Pericytes Cells |
Rabbit Cerebrovascular Pericytes from Ace Therapeutics are isolated from the brain tissue of a pathogen-free New Zealand White Rabbit. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
BBM-C-129 | Rat Brain Microvascular Endothelial Cells |
Rat Primary Brain Microvascular Endothelial Cells (RPBECs) from Ace Therapeutics are isolated from the brain tissue of 1-day-old neonatal Sprague-Dawley rats. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
BBM-C-149 | Bovine Astrocytes |
Bovine astrocytes from Ace Therapeutics are isolated from the bovine brain and are cryopreserved at passage one. Bovine astrocytes are characterized by immunofluorescence with antibody specific to GFAP. Each vial contains at least 0.5×10^6 cells per ml and is delivered frozen.
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inquiry |
BBM-C-134 | Rabbit Brain Microvascular Endothelial Cells |
Rabbit Brain Microvascular Endothelial Cells from Ace Therapeutics are isolated from the brain tissue of a pathogen-free New Zealand White Rabbit. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
|
inquiry |
BBM-C-139 | CD1 Mouse Astrocytes |
CD1 Mouse Astrocytes from Ace Therapeutics are isolated from postnatal day 2 mouse brains. MA is characterized by immunofluorescence with antibodies specific to GFAP. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |
BBM-C-138 | C57BL/6 Mouse Astrocytes |
C57BL/6 Mouse Astrocytes from Ace Therapeutics are isolated from brain tissues of pathogen-free laboratory mice. Each vial contains at least 1×10^6 cells per ml and is delivered frozen.
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inquiry |