Human Blood-Brain Barrier Model from Ace Therapeutics is developed by culturing brain endothelial cells with pericytes and astrocytes layered in an insert. The model mimics transport properties of the Blood Brain Barrier (BBB) due to the formation of tight junctions, higher expression of specific carriers, or great cell viability. Compared with the monoculture model, our 3D in vivo model of the BBB can truly mimic the BBB by enhancing the polarization of endothelial cells, facilitating the formation of tight junctions, promoting essential endothelial cell-to-cell contact for barrier development, and preventing the dilution of secreted neurotrophic factors.

3D Human Blood-Brain Barrier Modeling Kit with HBMEC from Ace Therapeutics is developed by culturing human brain microvascular endothelial cells (HBMEC), brain vascular pericytes, and astrocytes at a 1:1:1 ratio. Our Models come with media, and you can also order additional media. We provide a series of 3D BBB model culture substrates, such as collagens and hydrogels, for you.

Caco-2 Blood Brain Barrier Modeling Kit from Ace Therapeutics is developed by seeding with 21 days of differentiated and polarized Caco-2 cells on the Transwell insert plates. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.

Ready-to-Use Blood-Brain Barrier Modeling Kit from Ace Therapeutics is developed by co-culturing three cell types, primary cultures of rat (Wistar rat) brain capillary endothelial cells, brain pericytes, and astrocytes, which is an in vitro reconstituted BBB model and shows many of the in vivo BBB features. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.

MDCKII Blood Brain Barrier Modeling Kit from Ace Therapeutics is developed by seeded with 21 days differentiated and polarized Caco-2 and HT-29 cells with an absorptive and mucus-secreting phenotype, respectively on transwell insert plates. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.