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Human Blood-Brain Barrier Model
Cat.#: BBM-M-001
Specifications
Description Human Blood-Brain Barrier Model from Ace Therapeutics is developed by culturing brain endothelial cells with pericytes and astrocytes layered in an insert. The model mimics transport properties of the Blood Brain Barrier (BBB) due to the formation of tight junctions, higher expression of specific carriers, or great cell viability.
Compared with the monoculture model, our 3D in vivo model of the BBB can truly mimic the BBB by enhancing the polarization of endothelial cells, facilitating the formation of tight junctions, promoting essential endothelial cell-to-cell contact for barrier development, and preventing the dilution of secreted neurotrophic factors.Size 1 kit Species Human Storage Keep frozen in liquid nitrogen until plating. Shipping Ace Therapeutics ships Transwell models using dry ice. Applications In vivo like assays.
SARS-CoV2 research.
COVID-19 research.Citation Guidance If you use our product in a scientific publication, please cite it as "Ace Therapeutics Cat.#". Click here to submit your paper's PubMed ID (PMID) to receive rewards. Related Products
Cat.# Name Description Price BBM-M-006 Ready-to-Use Blood-Brain Barrier Modeling Kit Ready-to-Use Blood-Brain Barrier Modeling Kit from Ace Therapeutics is developed by co-culturing three cell types, primary cultures of rat (Wistar rat) brain capillary endothelial cells, brain pericytes, and astrocytes, which is an in vitro reconstituted BBB model and shows many of the in vivo BBB features. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.inquiry BBM-M-002 Human Blood-Brain Barrier Modeling Kit Human Blood-Brain Barrier Modeling Kit from Ace Therapeutics co-cultures endothelial cells, pericytes, and astrocytes in a collagen I matrix with a defined serum-free medium to replicate intercellular interactions at the BBB. Our Models come with media, and you can also order additional media. We provide a series of 3D BBB model culture substrates, such as collagens and hydrogels, for you.inquiry BBM-M-003 3D Human Blood-Brain Barrier Modeling Kit with HBMEC 3D Human Blood-Brain Barrier Modeling Kit with HBMEC from Ace Therapeutics is developed by culturing human brain microvascular endothelial cells (HBMEC), brain vascular pericytes, and astrocytes at a 1:1:1 ratio. Our Models come with media, and you can also order additional media. We provide a series of 3D BBB model culture substrates, such as collagens and hydrogels, for you.inquiry BBM-M-005 MDCKII Blood Brain Barrier Modeling Kit MDCKII Blood Brain Barrier Modeling Kit from Ace Therapeutics is developed by seeded with 21 days differentiated and polarized Caco-2 and HT-29 cells with an absorptive and mucus-secreting phenotype, respectively on transwell insert plates. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.inquiry BBM-M-004 Caco-2 Blood Brain Barrier Modeling Kit Caco-2 Blood Brain Barrier Modeling Kit from Ace Therapeutics is developed by seeding with 21 days of differentiated and polarized Caco-2 cells on the Transwell insert plates. Our Models come with media, and you can also order additional media. We provide a series of 3D organoid BBB model culture substrates, such as collagens and hydrogels, for you.inquiry All of our products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
Ace Therapeutics is a global leading provider of stroke research services. We are committed to accelerating progress in stroke research and drug development.
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