Brain Imaging Services in Animal Models of Stroke

Acute brain injury after stroke causes significant changes in the brain that can be observed by various neuroimaging techniques. These small animal noninvasive imaging techniques play an important role in the assessment of physiological and pathophysiological processes and can provide meaningful information for the research and diagnosis of stroke.

Fig. 1. Optical neuroimaging strategies to target the stroke pathology and regeneration processes upon stem cell grafting. (Aswendt et al., 2014)

Our Brain Imaging Services in Animal Models of Stroke

Ace Therapeutics is a leading provider of cutting-edge brain imaging services, offering reliable imaging techniques to image the ischemic brain in animal models of stroke. Our optical imaging technologies range from microscopy for examining cultured cells, tissue sections, or larger tissue samples, to in vivo microscopy for visualization of surface structures in living animals, to non-invasive imaging for whole-body imaging in small animals. Our highly skilled professionals and advanced technology platforms ensure reliable results for you.

We can perform in vivo imaging of stroke small animals, as well as obtaining brain tissue for in vitro imaging upon request. Below are our preclinical brain imaging methods.

• Fluorescence Imaging (FI)
• Bioluminescence Imaging (BLI)
• Magnetic Resonance Imaging (MRI)
• Photoacoustic Imaging (PAI)
• Laser Speckle Contrast Imaging (LSCI)
• Functional Ultrasound Imaging
• Micro-computed Tomography (Micro-CT) Imaging
• Positron Emission Tomography (PET) Imaging
• Single-photon Emission Computed Tomography (SPECT) Imaging

Applications of Brain Imaging in Animal Models of Stroke

We help our clients conduct a variety of studies using brain imaging technologies, including

• Analyzing the potential of stroke regeneration and transplantation of stem cells in preclinical trials.
• Studying stroke pathophysiology.
• Identifying suitable targets or test candidate compounds for stroke.
• Developing diagnostic imaging probes for stroke.

Ace Therapeutics provides reliable imaging technology for preclinical studies to understand stroke mechanisms and develop diagnostic or therapeutic modalities. Our brain imaging services enable detailed visualization of post-stroke brain structural and functional changes at high spatial resolution. Small animal imaging can be easily combined with other testing modalities to provide a set of multimodal endpoints. If you are interested in our services, please do not hesitate to contact us!

1. Aswendt, M., Adamczak, J., & Tennstaedt, A. (2014). A review of novel optical imaging strategies of the stroke pathology and stem cell therapy in stroke. Frontiers in cellular neuroscience, 8, 226.