In vivo pharmacodynamic assays are essential for the development of safe and effective antipsychotics. Ace Therapeutics is dedicated to providing comprehensive in vivo pharmacodynamic evaluation services to our clients. We utilize a multi-faceted approach, integrating animal models, behavioral testing, and advanced in vivo pharmacodynamic assays, to deliver high-quality in vivo pharmacodynamic assessment services to our clients. Our streamlined one-stop service is designed to assist clients in screening potential antipsychotics and providing insights into their mechanism of action.

Our In Vivo Efficacy Assessment Service of Antipsychotics

Ace Therapeutics develops models of psychiatric disorders by selecting appropriate animals, typically rodents. We then develop customized drug delivery strategies and perform behavioral testing for antipsychotic drug studies in laboratory rodents based on client needs. Furthermore, we collect blood and tissue samples from the animals to determine drug concentrations in the body and to assess the efficacy and effects of the drugs on specific genes, neurotransmitters, nerve cells, and neural circuits. Finally, we analyze and interpret the data to ensure that we provide our clients with comprehensive efficacy and safety data, as well as any other information they may require.

Our Capabilities

• Animal modeling service for psychiatric diseases

Our experienced experts will provide customized animal models to simulate specific psychiatric disorders, including animal models of depression, animal models of anxiety, animal models of schizophrenia, etc., based on your needs and drug properties. In addition, we ensure construct validity, apparent validity and predictive validity of animal models through model optimization and validation.

• Behavioral tests

Behavioral testing is an essential tool for assessing the safety of antipsychotic drug candidates, evaluating their efficacy, identifying potential adverse effects, and gaining insight into the underlying mechanisms of behavior and disease. Ace Therapeutics employs behavioral testing and behavioral observations in animal models to evaluate the effects of antipsychotic drug candidates on aspects of cognitive functioning, emotion regulation, and behavioral responses.

• In vivo pharmacodynamic characterization services for antipsychotic drugs

We assess the pharmacodynamic properties of drugs by measuring biochemical indicators related to drug action, such as neurotransmitter levels and receptor affinity.

Our Advanced Technologies

• Molecular biology techniques
• Histological techniques
• Electroencephalography
• Electrophysiology analysis
• Animal behavioral testing

Ace Therapeutics is committed to utilizing our extensive expertise and experience to provide comprehensive in vivo pharmacodynamic assessment services to our clients. Our one-stop solution includes evaluating a drug's affinity for specific neurotransmitter receptors, its effect on nerve conduction pathways, its ameliorative effect on behavioral symptoms, and more. With our expertise in antipsychotic drug discovery and development, you will have access to accurate and reliable in vivo pharmacodynamic data to help you make informed decisions in antipsychotic drug development. Please contact us for more details and we will be happy to assist you.