Tubulysin M

Cat. No.: IBDI-430474

Tubulysin M is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin M is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.

Product Details

Target	Microtubule/Tubulin | Apoptosis
Molecular Weight	727.95
Appearance	Solid
SMILES	O=C(N[[email protected]@H]([[email protected]@H](C)CC)C(N(C)[[email protected]@H](C(C)C)C[[email protected]@H](OC(C)=O)C1=NC(C(N[[email protected]@H](CC2=CC=CC=C2)C[[email protected]](C)C(O)=O)=O)=CS1)=O)[[email protected]@H]3N(C)CCCC3
Structure Classification	Ketones, Aldehydes, Acids
Purity	≥96.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.