Tubulysin H

Cat. No.: IBDI-430475

Tubulysin H is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Tubulysin H is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis.

Product Details

Target	Microtubule/Tubulin | Apoptosis
Molecular Weight	785.99
SMILES	O=C(N[[email protected]@H]([[email protected]@H](C)CC)C(N(COC(C)=O)[[email protected]@H](C(C)C)C[[email protected]@H](OC(C)=O)C1=NC(C(N[[email protected]@H](CC2=CC=CC=C2)C[[email protected]](C)C(O)=O)=O)=CS1)=O)[[email protected]@H]3N(C)CCCC3
Structure Classification	Ketones, Aldehydes, Acids

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.