Spadin TFA

Cat. No.: IBDI-438322

Spadin TFA, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with an IC50 value of 10 nM. Spadin TFA enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis. Spadin TFA can be used for antidepressant research.

Product Details

Target	Potassium Channel | 5-HT Receptor
Molecular Weight	2126.36
Appearance	Solid
Sequence Shortening	YAPLPRWSGPIGVSWGLR
Purity	99.73%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -80°C/2 years; -20°C/1 year *In solvent : -80°C, 6 months; -20°C, 1 month
Handling	Sealed storage, away from moisture and light
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.