Sanggenon C

Cat. No.: IBDI-430277

Sanggenon C is a flavanone Diels-Alder adduct compound, which is isolated from Cortex Mori (Sang Bai Pi). Sanggenon C exerts protective effects against cardiac hypertrophy and fibrosis via suppression of the calcineurin/NFAT2 pathway. Sanggenon C inhibits inducible nitric oxide synthase expression in RAW264.7 cells, and tumor necrosis factor-α-stimulated cell adhesion and vascular cell adhesion molecule-1 expression, by suppressing NF-κB activity. Sanggenon C possesses antioxidant, anti-inflammatory activities and inhibits Pancreatic lipase (PL) with the an IC50 of 3.00 μM.

Product Details

Target	NF-κB
Molecular Weight	708.71
Appearance	Solid
SMILES	C/C(C)=C/C[[email protected]](C1=CC=C(O)C=C1O2)(OC3=CC(O)=C([[email protected]@H](C=C(C)C[[email protected]@H]4C(C=CC(O)=C5)=C5O)[[email protected]@H]4C(C(C=CC(O)=C6)=C6O)=O)C(O)=C3C7=O)[[email protected]]27O
Structure Classification	Flavonoids>Flavanonols Phenols>Polyphenols

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.