Inquiry

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Rhoifolin

Cat. No.: IBDI-430284

Rhoifolin is a flavone glycoside can be isolated from Rhus succedanea. Rhoifolin has anti-diabetic effect acting through enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and glucose transporter 4 (GLUT 4) translocation. Rhoifolin has an anti-inflammatory action via multi-level regulation of inflammatory mediators. Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways. Rhoifolin also has cytotoxic activity against different cancer cell lines.

Size (Solid):

Product Details

Target Insulin Receptor | GLUT | NF-κB | p38 MAPK | Autophagy
Molecular Weight 578.52
Appearance Solid
SMILES O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[[email protected]](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]3O)[[email protected]@H]3O[[email protected]@](O[[email protected]@H](C)[[email protected]](O)[[email protected]]4O)([H])[[email protected]@H]4O)=C5)C2=C5O
Structure Classification Flavonoids>Flavones
Purity 99.24%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.