Resolvin E1

Cat. No.: IBDI-430434

Resolvin E1 (RvE1), a potent endogenous pro-resolving mediator of inflammation, is derived from omega-3 fatty acid eicosapentaenoic acid (EPA). Resolvin E1 is endogenously biosynthesized from EPA in the presence of Aspirin during the spontaneous resolution phase of acute inflammation, where specific cell-cell interactions occur. Resolvin E1 possesses unique counterregulatory actions that inhibit polymorphonuclear leukocyte (PMN) transendothelial migration. Resolvin E1 also acts as a potent inhibitor of leukocyte infiltration, dendritic cell migration, and IL-12 production.

Product Details

Target	Endogenous Metabolite
Molecular Weight	350.45
Appearance	Liquid
Synonyms	RvE1
SMILES	CC[[email protected]@H](O)/C=C/C=C\C[[email protected]@H](O)/C=C/C=C/C=C\[[email protected]@H](O)CCCC(O)=O
Structure Classification	Ketones, Aldehydes, Acids
Purity	≥95.0%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.