Cat. No.: IBDP-531774
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Online InquiryTarget Information
| Sequence | Recombinant Rat IL-1a is a 17.7 kDa protein containing 155 amino acid residues: MAPHSFQNNL RYKLIRIVKQ EFIMNDSLNQ NIYV DMDRIH LKAASLNDLQ LEVKFDMYAYSSGGDSKYPV TLKVSNTQLF VSAQGEDKPV LLKEIPETPK LITGSETDLI FFWEKINSKNYFTSAAF PEL LIATKEQSQV HLARGLPSMI DFQIS |
| Sequence Similarities | Belongs to the IL-1 family. |
| Cellular Localization | Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
| Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |
Product Details
| Product Type | Protein |
| Species | Rat |
| Source | E. coli |
| Protein Length | Full length protein |
| Purity | >98% |
| Active | Yes |
| Animal free | No |
| Nature | Recombinant |
| Application | FuncS, SDS-PAGE |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C. |
| Handling | Avoid freeze / thaw cycle. |