Recombinant Mouse RP105 Protein

Target Information

Sequence	MAPDISCFFL VALFLASCRA TTSSDQKCIE KEVNKTYNCE NLGLNEIPGT LPNSTECLEF SFNVLPTIQN TTFSRLINLT FLDLTRCQIY WIHEDTFQSQ HRLDTLVLTA NPLIFMAETA LSGPKALKHL FFIQTGISSI DFIPLHNQKT LESLYLGSNH ISSIKLPKGF PTEKLKVLDF QNNAIHYLSK EDMSSLQQAT NLSLNLNGND IAGIELGAFD SAVFQSLNFG GTQNLLVIFK GLKNSTIQSL WLGTFEDMDD EDISPAVFEG LCEMSVESIN LQKHYFFNIS SNTFHCFSGL QELDLTATHL SELPSGLVGL STLKKLVLSA NKFENLCQIS ASNFPSLTHL SIKGNTKRLE LGTGCLENLE NLRELDLSHD DIETSDCCNL QLRNLSHLQS LNLSYNEPLS LKTEAFKECP QLELLDLAFT RLKVKDAQSP FQNLHLLKVL NLSHSLLDIS SEQLFDGLPA LQHLNLQGNH FPKGNIQKTN SLQTLGRLEI LVLSFCDLSS IDQHAFTSLK MMNHVDLSHN RLTSSSIEAL SHLKGIYLNL ASNRISIILP SLLPILSQQR TINLRQNPLD CTCSNIYFLE WYKENMQKLE DTEDTLCENP PLLRGVRLSD VTLSCS
Sequence Similarities	Belongs to the Toll-like receptor family. Contains 19 LRR (leucine-rich) repeats. Contains 1 LRRCT domain.
Amino Acids	1 to 626
Cellular Localization	Cell membrane.
Tissue Specificity	Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
Function	May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.

Product Details

Product Type	Protein
Species	Mouse
Source	HEK 293 Cells
Tag	His
Endotoxin Level	<1.0 Eu/µg
Protein Length	Protein fragment
Molecular Weight	69 kDa
Purity	>92%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at Room Temperature.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.