Recombinant Mouse DNER Protein

Target Information

Sequence	MPPRRAQAPGAPLLPVLALLPLLLGAGPQSGCLASPVSAAPLPAPGPCAS QPCRNGGVCTPRSVTDQEHPAADAEPRYSCTCPAGVSGTYCQFVADPCAS NPCHHGNCSSSSSSSSDSYLCICNDGYEGLNCEQPLPSIPTSGWTESTAP RQLQPVPATQEPDIILPRSQATVTLPTWQPKTGQKVVEMKWDQVEVVPDV ACGNASSNNSAGGRLVSFEVPQNTSVKIRQDANSLLILLWKVTATGFQQC SLIDGRSVTPLQAPGGLVLLEEMLALGPNHFIGFVNDSVAKSIVALRLTL VVKASNCVPGDSHSNDLECSGKGKCATKPSEATFSCTCQDQYIGTFCEEF DACQRKPCQNEASCIDANEKQDGSNFTCLCLPGYTGELCQSKIDYCVLDP CRNGATCVSSLSGFTCQCLEGYFGSACEEKVDPCMSSPCQNNGTCYVDGV HFTCSCSPGFTGPTCAQLVDFCALSPCAHGMCRSVGTSYKCLCDPGYHGL YCEEEYNECLSAPCLNAATCRDLINGYECVCLAEYKGTHCELYKDPCANI SCLNGGTCDSEGLNGTCICAPGFTGEECDIDINECDSNPCHHAGTCLDQP NGYTCHCPHGWVGANCEIHLQWKSGHMAESLTNMPRHSLY
Sequence Similarities	Contains 10 EGF-like domains. Contains 1 follistatin-like domain.
Amino Acids	1 to 640
Cellular Localization	Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region (By similarity).
Tissue Specificity	Expressed in brain, spinal cord and adrenal gland.
Function	Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.

Product Details

Product Type	Protein
Species	Mouse
Source	HEK 293 Cells
Endotoxin Level	<0.1 Eu/μg
Protein Length	Protein fragment
Molecular Weight	68 kDa
Purity	≥85%
Active	No
Animal free	No
Nature	Recombinant
Application	SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.