Cat. No.: IBDP-530740
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Online InquiryTarget Information
| Sequence | MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLWLKSPGRFE RILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTG FTSFGLLKL |
| Sequence Similarities | Belongs to the tumor necrosis factor family. |
| Amino Acids | 113 to 261 |
| Cellular Localization | Secreted and Cell membrane. |
| Tissue Specificity | Specifically expressed on activated CD4+ T-lymphocytes. |
| Function | Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching.Release of soluble CD40L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway. |
Product Details
| Product Type | Protein |
| Species | Human |
| Source | E. coli |
| Endotoxin Level | <0.1 Eu/μg |
| Protein Length | Full length protein |
| Molecular Weight | 16 kDa |
| Purity | >98% |
| Active | Yes |
| Animal free | Yes |
| Nature | Recombinant |
| Application | FuncS, HPLC, SDS-PAGE |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C. |
| Handling | Avoid freeze / thaw cycle. |