Recombinant Human PIK3C2B Protein

Target Information

Sequence	WTHMNHQDAL GLLHATFPDQ EVRRMAVQWI GSLSDAELLD YLPQLVQALK YECYLDSPLV RFLLKRAVSD LRVTHYFFWL LKDGLKDSQF SIRYQYLLAA LLCCCGKGLR EEFNRQCWLV NALAKLAQQV REAAPSARQG ILRTGLEEVK QFFALNGSCR LPLSPSLLVK GIVPRDCSYF NSNAVPLKLS FQNVDPLGEN IRVIFKCGDD LRQDMLTLQM IRIMSKIWVQ EGLDMRMVIF RCFSTGRGRG MVEMIPNAET LRKIQVEHGV TGSFKDRPLA DWLQKHNPGE DEYEKAVENF IYSCAGCCVA TYVLGICDRH NDNIMLKTTG HMFHIDFGRF LGHAQMFGNI KRDRAPFVFT SDMAYVINGG DKPSSRFHDF VDLCCQAYNL IRKHTHLLLN LLGLMLSCGI PELSDLEDLK YVYDALRPQD TEANATTYFT RLIESSLGSV ATKLNFFIHN LAQMKFTGSD DRLTLSFASR THTLKSSGRI SDVFLCRHEK IFHPNKGYIY VVKVMRENTH EATYIQRTFE EFQELHNKLR LLFPSSHLPS FPSRFVIGRS RGEAVAERRR EELNGYIWHL IHAPPEVAEC DLVYTFFHPL PRDEKAMGTS PAPKSSDGTW ARPVGKVGGE VKLSISYKNN KLFIMVMHIR GLQLLQDGND PDPYVKIYLL PDPQKTTKRK TKVARKTCNP TYNEMLVYDG IPKGDLQQRE LQLSVLSEQG FWENVLLGEV NIRLRELDLA QEKTGWFALG SRSHGTL
Sequence Similarities	Belongs to the PI3/PI4-kinase family. Contains 1 C2 domain. Contains 1 C2 PI3K-type domain. Contains 1 PI3K-RBD domain. Contains 1 PI3K/PI4K domain. Contains 1 PIK helical domain. Contains 1 PX (phox homology) domain.
Amino Acids	850 to 1606
Cellular Localization	Microsome. Cell membrane. Cytoplasm, cytosol. Nucleus. Endoplasmic reticulum. Found mostly in the microsome, but also in the plasma membrane and cytosol. Nuclear in testis.
Tissue Specificity	Expressed in columnar and transitional epithelia, mononuclear cells, and ganglion cells (at protein level). Widely expressed, with highest levels in thymus and placenta and lowest in peripheral blood, skeletal muscle and kidney.
Function	Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades.

Product Details

Product Type	Protein
Species	Human
Source	Baculovirus Infected Sf9 Cells
Tag	GST
Protein Length	Protein fragment
Purity	>70%
Active	Yes
Animal free	No
Nature	Recombinant
Application	FuncS, SDS-PAGE

Storage & Handling

Shipping	Shipped with Dry Ice.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.