Cat. No.: IBDP-531177
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Online InquiryTarget Information
| Sequence Similarities | Belongs to the ZC3H12 family. Contains 1 C3H1-type zinc finger. |
| Amino Acids | 234 to 503 |
| Cellular Localization | Cytoplasm. Nucleus. |
| Function | Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untranslated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA (By similarity). Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. |
Product Details
| Product Type | Protein |
| Species | Human |
| Source | E. coli |
| Protein Length | Protein fragment |
| Molecular Weight | 29 kDa |
| Purity | >50% |
| Active | No |
| Animal free | No |
| Nature | Recombinant |
| Application | SDS-PAGE |
Storage & Handling
| Shipping | Shipped at 4 °C. |
| Storage | Store at -20 °C. |
| Handling | Avoid freeze / thaw cycle. |