Recombinant Human MCP2 Protein

Target Information

Sequence	MCAF/ MCP-1 is an 8.6 kDa protein containing 76 amino acid residues: QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADP KERWVRDSMKHLDQI FQNLKP
Sequence Similarities	Belongs to the intercrine beta (chemokine CC) family.
Cellular Localization	Secreted.
Tissue Specificity	Highest expression found in the small intestine and peripheral blood cells. Intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas. Low levels seen in the brain, liver, spleen and prostate.
Function	Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.

Product Details

Product Type	Protein
Species	Human
Source	E. coli
Endotoxin Level	<0.1 Eu/μg
Protein Length	Full length protein
Purity	>97%
Active	Yes
Animal free	No
Nature	Recombinant
Application	FuncS, SDS-PAGE

Storage & Handling

Shipping	Shipped at 4 °C.
Storage	Store at -20 °C.
Handling	Avoid freeze / thaw cycle.