Cat. No.: IBDP-531280
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Online InquiryTarget Information
Synonyms | rHuIFN-λ1/IL-29|||IL-29|||IFN-lambda-1|||Cytokine Zcyto21|||Interleukin-29 |
Sequence | GPVPTSKPTTTGKGCHIGRFKSLSPQELASFKKARDALEESLKLKNWSCSSPVFPGNWDLRLLQVRERPVALEAELALTLKVLEAAAGPALEDVLDQPLHTLHHILSQLQACIQPQPTAGPRPRGRLHHWLHRLQEAPKKESAGCLEASVTFNLFRLLTRDLKYVADGNLCLRTSTHPEST |
Function | IFN-lambda 1 (IL-29) is a member of the Type-III interferon family. IFN-lambda 1 signals through a heterodimeric receptor complex comprising IFNλ receptor 1 (IFNLR1) and IL-10 receptor subunit-β (IL-10RB). When IFN-lambda 1 binds with the receptor complex, Jak1 and Tyk2 will be activated, and leads to subsequent tyrosine phosphorylation of the IFN-λR1, and activation of STAT1 and STAT2. IFN-lambda 1 modulates immunity in infections and autoimmune diseases. IFN-lambda 1/IL-29 Protein is a recombinant human IFN-lambda 1 (G20-T200) without any tag, which is produced in E. coli. |
Product Details
Product Type | Protein |
Species | Human |
Source | E. coli |
Tag | Tag Free |
Endotoxin Level | <1.0 Eu/µg |
Molecular Weight | 19.8 kDa |
Purity | ≥95% |
Storage & Handling
Shipping | Shipped at Room Temperature. |
Storage | Store at -20 °C. |
Handling | Avoid freeze / thaw cycle. |