Cat. No.: IBDP-531627
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Online InquiryTarget Information
Sequence | Recombinant Human NAP-2 is a 7.6 kDa protein containing 70 amino acid residues: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KD GRKICLDP DAPRIKKIVQKKLAGDESAD |
Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
Cellular Localization | Secreted. |
Function | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. |
Product Details
Product Type | Protein |
Species | Human |
Source | E. coli |
Endotoxin Level | <0.1 Eu/μg |
Protein Length | Full length protein |
Purity | >98% |
Active | No |
Animal free | No |
Nature | Recombinant |
Application | FuncS, SDS-PAGE |
Storage & Handling
Shipping | Shipped at 4 °C. |
Storage | Store at -20 °C. |
Handling | Avoid freeze / thaw cycle. |