Cat. No.: IBDP-530732
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Online InquiryTarget Information
Sequence | QNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDP HKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTC LDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVG PALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNA SCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSM KTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACH YNCPGDNDIFESLYYRKMYGDMA |
Sequence Similarities | Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. |
Amino Acids | 27 to 349 |
Cellular Localization | Secreted > extracellular space > extracellular matrix. Secreted. |
Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
Product Details
Product Type | Protein |
Species | Human |
Source | HEK 293 Cells |
Protein Length | Full length protein |
Molecular Weight | 36 kDa |
Purity | ≥95% |
Active | No |
Animal free | Yes |
Nature | Recombinant |
Application | SDS-PAGE |
Storage & Handling
Shipping | Shipped at Room Temperature. |
Storage | Store at Room Temperature. |
Handling | Avoid freeze / thaw cycle. |