Recombinant Human 4-1BB/TNFRSF9 Protein

Target Information

Synonyms

CD137|||TNFRSF9|||4-1BB ligand receptor|||41BB|||4-1BB|||CDw137|||FLJ43501|||ILA|||T cell antigen ILA

Function

4-1BB (CD137; TNFRSF9), a receptor of TNFSF9/4-1BBL, belongs to the tumor necrosis factor (TNF) receptor superfamily. 4-1BB is helpful for T cell activation and development, and also induces peripheral mononuclear cell proliferation and migration to the tumor microenvironment. 4-1BB is also involved in enhancing Nrf2 and NF-κB pathway mediated apoptosis of endothelial cells. Human 4-1BB protein is a surface glycoprotein with a transmembrane domain (187-213 a.a.). 4-1BB/TNFRSF9 Protein (Biotinylated, HEK293, Fc-Avi) is the extracellular part (L24-Q186) of 4-1BB protein, produced by HEK293 cells with C-terminal Avi- and hFc-tag.

Product Details

Product Type	Protein
Species	Human
Source	HEK 293 Cells
Tag	Avi, hFc
Endotoxin Level	<1.0 Eu/µg
Molecular Weight	60-70 kDa
Purity	≥95%

Storage & Handling

Shipping	Shipped with Dry Ice.
Storage	Store at -20 °C or -80 °C.
Handling	Avoid freeze / thaw cycle.