Rat CTGF ELISA Kit

Overview

Sample Type	Serum, Cell culture media, EDTA Plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Secreted Molecules
Sensitivity	0.12 ng/ml
Range	0.16 ng/ml - 10 ng/ml
Species Reactivity	Reacts with: Rat
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Tissue Specificity	Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Sequence Similarities	Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain.
Cellular Localization	Secreted > extracellular space > extracellular matrix. Secreted.

Storage & Handling

Storage

Store at +4°C. Please refer to protocols.