RARγ Reporter Cellular Assay Pack

Product Details

Synonyms	RAR Gamma, Retinoic Acid Receptor Gamma, RARG
Description	The RARγ Reporter Cellular Assay Pack provides all the key reagents required to monitor the activity of retinoic acid receptor gamma (RARγ). The pack contains the RARγ Reporter (Luc)-HEK293 Cell Line, a luciferase reporter cell line that contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARγ (GenBank Accession No. P13631-1). This cell line is functionally validated for the response to the stimulation of all-trans retinoic acid, and the expression of RARγ is confirmed by Western blotting.
Applications	Monitor RARγ-regulated pathway activityScreen agonists or antagonists of RARγ.
Materials Required But Not Supplied	• All-Trans Retinoic Acid (ATRA) : stock solution in DMSO • 96-well tissue culture treated white clear-bottom assay plate • Luminometer
Scientific Category	Cell Signaling Pathway

Storage & Handling

Storage/Stability	Stable at least 12 months from date of receipt, when stored as directed (-20°C).
Shipping Temperature	-80°C
Warnings	Avoid freeze/thaw cycles
Regulatory Status	Research Use Only