Polyphyllin VI

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Cat. No.: IBDI-431031

Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target	Apoptosis \| Pyroptosis
Molecular Weight	738.90
Appearance	Solid
SMILES	O[[email protected]]1([[email protected]@]2([H])O[[email protected]]3(CC[[email protected]@H](C)CO3)[[email protected]]1C)[[email protected]]([[email protected]@]4([H])C2)(CC[[email protected]@]5([H])[[email protected]@]4([H])CC=C6[[email protected]@]5(CC[[email protected]](O[[email protected]@](O[[email protected]](CO)[[email protected]@H](O)[[email protected]@H]7O)([H])[[email protected]@H]7O[[email protected]@](O[[email protected]@H](C)[[email protected]](O)[[email protected]]8O)([H])[[email protected]@H]8O)C6)C)C
Structure Classification	Steroids
Purity	98.41%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Powder: -20°C/3 years; 4°C/2 years In solvent: -80°C/6 months; -20°C/1 month
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.

! For research use only, not intended for any clinical use.