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Phospho-c-Jun (S63) and Total c-Jun ELISA Kit

Cat. No.: IBDAK-620153

Size:

Overview

Sample Type Cell Lysate
Detection Method Colorimetric
Assay Type Semi-quantitative
Assay Duration Multiple steps standard assay
Product Type TLR Signaling
Species Reactivity Reacts with: Mouse
Platform Pre-coated microplate (12 x 8 well strips)

Target

Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the USP28 promoter in colorectal cancer (CRC) cells (PubMed:24623306).
Sequence Similarities Belongs to the bZIP family. Jun subfamily. Contains 1 bZIP (basic-leucine zipper) domain.
Cellular Localization Nucleus.

Storage & Handling

Storage Store at +4°C.
Storage Buffer Constituent: 100% PBS
! For research use only, not intended for any clinical use.
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