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* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Phorbol 12-myristate 13-acetate

Cat. No.: IBDI-430443

Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a dual SphK and protein kinase C (PKC) activator. Phorbol 12-myristate 13-acetate is a NF-κB activator. Phorbol 12-myristate 13-acetate induces differentiation in THP-1 cells.

Size (Solution): 10 mM * 1 mL in DMSO

Size (Solid + Solvent): 10 mM * 1 mL ready for reconstitution

Size (Solid):

Product Details

Target PKC | SphK | NF-κB
Molecular Weight 616.83
Appearance Solid
Synonyms PMA, TPA, Phorbol myristate acetate
SMILES CCCCCCCCCCCCCC(O[[email protected]]([[email protected]]1C)[[email protected]]2(OC(C)=O)[[email protected]@]([[email protected]@](C=C(CO)C[[email protected]]34O)([H])[[email protected]@]1(O)[[email protected]]4([H])C=C(C)C3=O)([H])C2(C)C)=O
Structure Classification Ketones, Aldehydes, Acids
Purity 99.29%

Storage & Handling

Shipping Room temperature in continental US. May vary elsewhere.
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.
! For research use only, not intended for any clinical use.
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