Cat. No.: IBDRGCL60464
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| Description | PAI-1 Reporter (Luc) –Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity. |
| Host Cell Line | Mv1 Lu Cells |
| Supplied As | Each vial contains ~ 2 x 106 cells in 1 mL of 10% DMSO |
| Materials Required But Not Supplied | • Human TGF-β1 • Thaw Medium 1 • Growth medium: Thaw Medium 1 + G418 700 µg/ml. • Assay medium: DMEM medium + 1% BSA + 1% Pen/Strep96-well tissue culture treated white clear-bottom assay plate • Luminometer |
| UniProt | P05121 |
| Mycoplasma Testing | The cell line has been screened using the PCR-based Mycoplasma Detection kit to confirm the absence of Mycoplasma species. |
| Scientific Category | Immunotherapy |
Storage & Handling
| Storage/Stability | Store in liquid nitrogen immediately upon receipt. |
| Shipping Temperature | -80°C |
| Warnings | Avoid freeze/thaw cycles |
| Regulatory Status | Research Use Only |