Ophiopogonin D

Cat. No.: IBDI-430989

Ophiopogonin D, isolated from the tubers of Ophiopogon japonicus, is a rare naturally occurring C29 steroidal glycoside. Ophiopogonin D is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation, IκBα down-regulation, intracellular Ca 2+ overload and activation of pro-inflammatory cytokines by increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs). Ophiopogonin D has been used to treat inflammatory and cardiovascular diseases for thousands of years.

Product Details

Target	PPAR | NF-κB | Calcium Channel
Molecular Weight	855.02
Appearance	Solid
SMILES	C[[email protected]@]12[[email protected]]([[email protected]@H]3C)([H])[[email protected]](O[[email protected]]34CC[[email protected]@H](C)CO4)([H])C[[email protected]@]1([H])[[email protected]@](CC=C5[[email protected]@]6([[email protected]@H](C[[email protected]](O)C5)O[[email protected]@](O[[email protected]](C)[[email protected]](O)[[email protected]@H]7O[[email protected]@](OC[[email protected]@H](O)[[email protected]@H]8O)([H])[[email protected]@H]8O)([H])[[email protected]@H]7O[[email protected]@](O[[email protected]@H](C)[[email protected]](O)[[email protected]]9O)([H])[[email protected]@H]9O)C)([H])[[email protected]]6([H])CC2
Structure Classification	Steroids
Purity	98.59%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.