Norartocarpetin

Cat. No.: IBDI-430280

Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells.

Product Details

Target	Tyrosinase | Ras | Raf | MAPKA | PK2 (MK2) | Apoptosis
Molecular Weight	286.24
Appearance	Solid
SMILES	O=C1C=C(C2=CC=C(O)C=C2O)OC3=CC(O)=CC(O)=C13
Structure Classification	Flavonoids>Flavones
Purity	98.92%

Storage & Handling

Shipping	Room temperature in continental US. May vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Regulatory Status	This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use.