Myeloperoxidase (MPO) Activity Assay Kit (Fluorometric)

Overview

Sample Type	Cell culture supernatant, Tissue Extracts
Detection Method	Fluorescent
Assay Type	Enzyme activity
Assay Time	30 min
Product Type	Macrophage / Inflamm.
Sensitivity	> 0.0005 mU/well
Species Reactivity	Reacts with: Mammals, Other species
Platform	Microplate reader

Target

Function	Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
Sequence Similarities	Belongs to the peroxidase family. XPO subfamily.
Cellular Localization	Lysosome.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.