Mouse uPA Receptor/U-PAR ELISA Kit

Overview

Sample Type	Cell culture supernatant, Serum, Cell Lysate, Hep Plasma, EDTA Plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	3 h 30 min
Assay Duration	Multiple steps standard assay
Product Type	Cell Type Markers
Sensitivity	< 5 pg/ml
Range	62.5 pg/ml - 4000 pg/ml
Species Reactivity	Reacts with: Mouse
Platform	Pre-coated microplate (12 x 8 well strips)

Target

Function	Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
Tissue Specificity	Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
Sequence Similarities	Contains 3 UPAR/Ly6 domains.
Cellular Localization	Secreted and Cell membrane.

Storage & Handling

Storage

Please refer to protocols.