Mouse P-Selectin ELISA Kit (CD62P)

Overview

Sample Type	Cell culture supernatant, Serum, Cell culture extracts, Cit plasma
Detection Method	Colorimetric
Assay Type	Sandwich (quantitative)
Assay Time	1 h 30 min
Assay Duration	One step assay
Product Type	Cell Type Markers
Sensitivity	4.16 pg/ml
Range	23.4 pg/ml - 1500 pg/ml
Species Reactivity	Reacts with: Mouse Does not react with: Goat, Cow, Pig
Platform	Microplate (12 x 8 well strips)

Target

Function	Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.
Tissue Specificity	Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
Sequence Similarities	Belongs to the selectin/LECAM family. Contains 1 C-type lectin domain. Contains 1 EGF-like domain. Contains 9 Sushi (CCP/SCR) domains.
Cellular Localization	Membrane.

Storage & Handling

Storage

Store at -20°C. Please refer to protocols.