Cat. No.: IBDAK-620347
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Sample Type | Cell culture supernatant, Serum |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 3 h 45 min |
Assay Duration | Multiple steps standard assay |
Product Type | Macrophage / Inflamm. |
Sensitivity | < 10 pg/ml |
Range | 15.6 pg/ml - 500 pg/ml |
Species Reactivity | Reacts with: Mouse |
Platform | Microplate |
Target
Function | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoeitic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. |
Sequence Similarities | Belongs to the IL-6 superfamily. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |