Cat. No.: IBDAK-620368
Size:
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Assay Type | ELISA set |
Product Type | Cell Type Markers |
Range | 62.5 pg/ml - 4000 pg/ml |
Species Reactivity | Reacts with: Mouse |
Platform | Reagents |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Target
Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
Sequence Similarities | Belongs to the immunoglobulin superfamily. ICAM family. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. |
Cellular Localization | Membrane. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | Constituent: 100% PBS |