Cat. No.: IBDAK-620428
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Assay Type | ELISA set |
Product Type | Chemokines |
Range | 62.5 pg/ml - 4000 pg/ml |
Species Reactivity | Reacts with: Mouse |
Platform | Reagents |
Application | Sandwich ELISA |
Properties
Carrier Free | Yes |
Target
Function | Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. |
Tissue Specificity | High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders. |
Sequence Similarities | Belongs to the intercrine alpha (chemokine CxC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. |
Storage Buffer | Constituent: 100% PBS |