Cat. No.: IBDAK-620434
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Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Duration | Multiple steps standard assay |
Product Type | Secreted Molecules |
Sensitivity | 0.1 ng/ml |
Range | 0.16 ng/ml - 10 ng/ml |
Species Reactivity | Reacts with: Mouse |
Platform | Microplate (12 x 8 well strips) |
Target
Function | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
Tissue Specificity | Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested. |
Sequence Similarities | Belongs to the CCN family. Contains 1 CTCK (C-terminal cystine knot-like) domain. Contains 1 IGFBP N-terminal domain. Contains 1 TSP type-1 domain. Contains 1 VWFC domain. |
Cellular Localization | Secreted > extracellular space > extracellular matrix. Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |