Cat. No.: IBDAK-620474
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Sample Type | Cell culture supernatant, Serum, Plasma, Cell culture extracts, Tissue Extracts |
Detection Method | Colorimetric |
Assay Type | Sandwich (quantitative) |
Assay Time | 1 h 30 min |
Assay Duration | One step assay |
Product Type | Chemokines |
Sensitivity | 4.7 pg/ml |
Range | 62.5 pg/ml - 4000 pg/ml |
Species Reactivity | Reacts with: Mouse Does not react with: Rat, Human |
Platform | Pre-coated microplate (12 x 8 well strips) |
Target
Function | Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. |
Tissue Specificity | Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin. |
Sequence Similarities | Belongs to the intercrine beta (chemokine CC) family. |
Cellular Localization | Secreted. |
Storage & Handling
Storage | Store at +4°C. Please refer to protocols. |